Lifestyle

Study finds non-heavy alcohol use associated with liver fibrosis

Liver disease is consistently associated with heavy alcohol consumption, but studies of non-heavy alcohol use on liver health are often contradictory, both within the general population and among those known to have non-alcoholic fatty liver disease (NAFLD) and at-risk individuals. While evidence suggests that the pattern of alcohol consumption may be an important predictor of […]

Lifestyle

Camizestrant may be superior to fulvestrant in patients with hormone receptor-positive, HER2-negative breast cancer

The next-generation selective estrogen receptor degrader (SERD) camizestrant improved progression-free survival, compared with fulvestrant (Faslodex), in patients with hormone receptor-positive, HER2-negative breast cancer in the phase II SERENA-2 trial, according to results presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022. Hormone receptor-positive, HER2-negative breast cancer is often treated with drugs that […]

Lifestyle

Circulating tumor cell count guidance may improve long-term outcomes for patients with metastatic breast cancer

The use of circulating tumor cell (CTC) count to guide the choice between chemotherapy and endocrine therapy as first-line therapy for patients with metastatic, estrogen receptor (ER)-positive/HER2-negative breast cancer provided overall survival benefit, compared with physician’s choice of treatment, according to data from the STIC CTC trial presented at the San Antonio Breast Cancer Symposium, […]

Lifestyle

Adding capivasertib to fulvestrant improves progression-free survival of hormone receptor-positive breast cancer

In patients with hormone receptor (HR)-positive, HER2-negative tumors resistant to aromatase inhibitors, addition of the investigational AKT inhibitor capivasertib to fulvestrant (Faslodex) doubled the median progression-free survival compared with placebo plus fulvestrant in the phase III CAPItello-291 clinical trial, according to results presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022. Patients […]

Lifestyle

Children’s on-road cycling safety sees ‘dramatic improvement’ after indoor immersive virtual reality training

Drifting off or losing concentration is a major cause of cycling accidents, and because they’re not as good as seeing hazards as adults, children are more often seriously hurt. Not looking properly at junctions and “human error” are the main cause of on-road cycling accidents according to The Department for Transport. Research backed by The […]

Lifestyle

Why mourning a pet can be harder than grieving for a person

Many pet owners know that our connections with animals can be on an emotional par with those we share with other humans—and scientific research backs this up. The key ingredients of human attachment are experiencing the other person as a dependable source of comfort, seeking them out when distressed, feeling enjoyment in their presence and […]

Lifestyle

New prostate cancer diagnostic pathway paves way for general screening

In screening for prostate cancer, the risk of overdiagnosis can be halved, a University of Gothenburg study shows. With the proposed diagnostic pathway, considerably fewer harmless tumors are found. This solves a big problem and makes general screening feasible. Researchers at Sahlgrenska Academy, part of Gothenburg University, and Sahlgrenska University Hospital performed the present study, […]